Wednesday, July 17, 2013

San Antonio attorney named to State Bar of Texas

Courtesy Strasburger & Price LLP

Elizabeth Copeland is the new chair of the tax section of the State Bar of Texas. She is a tax attorney with Strasburger & Price in San Antonio.

Elizabeth Copeland, a partner in the tax division of Strasburger & Price LLP, has been elected to a leadership position with the State Bar of Texas? tax section. As chair, she will oversee the programming that benefits more than 1,000 tax attorneys in the state.

?We are fortunate to have exemplary lawyers such as Elizabeth in our Tax Practice,? says John Round, chair of Strasburger?s tax practice. ?She demonstrates great dedication to her work, clients and the community.?

Copeland was instrumental in creating the sections? Tax Court Pro Bono Program. In her role as chair, she plans to continue and to expand the work of the program.

Copeland?s area of specialization is civil tax controversies.

Tricia Lynn Silva covers real estate, retail, construction, and law firms; she also plans and edits some special reports.

Source: http://feedproxy.google.com/~r/vertical_18/~3/rgScmcUL5Cs/san-antonio-attorney-named-to-state.html

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Monday, July 15, 2013

Apple Investigates China iPhone Death Allegations

Apple Inc. said Monday that it is investigating a case in which the family of a 23-year-old woman alleges that she was electrocuted by her iPhone.

Though details about the case remain sketchy, it has caught the imagination of social media users in China, who have been spreading word about the case and warning not to use devices while they are charging.

According to a report in China?s official state-run Xinhua news agency, relatives of the woman in China?s western Xinjiang Uighur Autonomous Region are alleging the woman died after trying to answer a call while her iPhone was charging. An officer with the local Public Security Bureau said Monday that an ?elementary inspection? showed the woman, named Ma Ailun, was electrocuted.

?Her neck had an obvious electronic injury,? he told China Real Time.

Beyond that, though, the official said that the case was still under investigation, and there were no more details available about whether her smartphone, the charger, or something else killed the woman.

In its statement, Apple said: ?We are deeply saddened to learn of this tragic incident and offer our condolences to the Ma family. We will fully investigate and cooperate with authorities in this matter.?

Official media quoted extensively from the microblog feed of a woman who they said was the sister of the victim, though her identity couldn?t be confirmed by China Real Time. She said that her sister had purchased the phone in December. She didn?t indicate whether the phone was Apple?s newest iPhone or an earlier model, and thus far local media reports have had conflicting reports about which model the iPhone might be.

While the fact are still unclear, a number of online users in China focused on the type of charger she might have used. The China Consumers? Association in May warned about the dangers of a ?flood? of uncertified power chargers on the market (in Chinese). In the release the association warned the chargers could turn a smartphone into a ?pocket grenade? and cause explosions, electric shock, or fires in a variety of electronic devices.

?Don?t talk such nonsense, it?s a five volt current, it couldn?t kill a cockroach,? wrote one microblogger. ?What is her house?s surge protector doing??

Another said using a phone while it is plugged in shouldn?t be a problem ?unless you?re using a shoddy transformer. Even if you do that the possibility of this happening is low.?

The case is the most recent in a string of public relations difficulties for Apple in China. In April the Communist Party mouthpiece the People?s Daily put the Cupertino, Calif., company?s app store on a list of websites being investigated for providing pornographic content in China. Earlier that same month, Apple Chief Executive Tim Cook issued an apology to its Chinese customers after the company?s warranty policy came under attack in state media.

? Paul Mozur. Follow him on Twitter @paulmozur

Like China Real Time on Facebook and follow us Twitter for the latest updates.

Source: http://blogs.wsj.com/chinarealtime/2013/07/15/apple-investigates-china-iphone-death-allegations/?mod=WSJBlog

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India: Man Abducts Estranged Wife, Cuts her 100 Times With Razor Blade

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Source: www.ibtimes.com --- Sunday, July 14, 2013
The man kept his estranged wife in seclusion for nine days leaving nearly 100 cuts on her body with a razor blade. ...

Source: http://www.ibtimes.comhttp:0//www.ibtimes.co.in/articles/490018/20130714/man-abducted-estranged-wife-100-cuts-india.htm

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Friday, July 12, 2013

Lilly plans big Alzheimer's disease study after prior failures

By Ransdell Pierson

(Reuters) - Despite two failed late-stage trials of its experimental Alzheimer's drug solanezumab, Eli Lilly and Co said on Friday it plans to run yet another study, this time focusing only on mild patients who appeared to respond to the treatment.

And the company will take extra steps to ensure it is testing actual Alzheimer's patients by pre-screening them with its imaging agent Amyvid to ensure they have deposits of the protein beta amyloid that is linked with the disease.

Solanezumab, which patients take by infusion, works by blocking the beta-amyloid protein that forms plaques in the brain signaling the onset of the disease. Bapineuzumab, a similar drug developed by Pfizer Inc, failed its main trial goals last year.

Lilly's two earlier trials of solanezumab had involved patients with mild to moderate symptoms. Combined data from those trials last summer showed the drug slowed cognitive decline by 34 percent in patients who started out with only mild symptoms, but without slowing declines in their ability to perform everyday tasks.

Lilly said the new Phase III trial will consist of 2,100 people, considerably more than the total of about 1,300 with mild Alzheimer's in the earlier two Phase III studies.

"Since Lilly saw a signal of benefit in the mild patients in the completed trials, it makes a lot of sense for them to simply zoom in on that group in this new trial," said Steven Ferris, director of the Alzheimer's Disease Center at NYU Langone Medical Center in New York. "It's a roll of the dice again, but they'll get a definitive answer."

Ferris said Lilly's decision to forge ahead with another trial was a bold move, but one worth taking because no current treatments slow progression of the disease.

"That's what we need."

The Indianapolis company plans to begin enrolling patients in the new study, called Expedition 3, before the end of September, and noted that patients would be treated for 18 months. But Lilly declined to speculate when it will have final data from the high-profile study.

An estimated 5 million Americans have Alzheimer's, the most common cause of dementia. More than 38 million people worldwide are believed to have dementia, including Alzheimer's disease, and those numbers are expected to rise as more people live longer.

WRONG PATIENTS SCREENED

Eric Siemers, senior medical director of Lilly's Alzheimer's program, said an estimated 25 percent of patients in the two earlier Expedition trials might not actually have had beta-amyloid deposits or Alzheimer's disease, so solanezumab could not have helped them.

He said many patients were enrolled in those trials on the basis of symptoms, without undergoing sophisticated diagnostic procedures now available to confirm the presence of beta-amyloid deposits.

In addition to using Amyvid, its new radioactive imaging agent, Siemers said the company will also look at biochemical measures in the spinal fluid can also help assess whether patients have Alzheimer's.

"This pre-screening will take Lilly longer to enroll patients, but is a wise move," Sanford Bernstein analyst Tim Anderson said in a research note. He said the earliest the drug is likely to reach the market, assuming the trial succeeds, is late 2017.

Maria Carrillo, vice president of scientific and medical affairs for the Alzheimer's Association, said the tighter screening will "strengthen" the new study. "When you're using an amyloid-based approach you want to make sure amyloid is there."

Lilly's renewed push behind solanezumab comes amid other recent setbacks for its Alzheimer's program.

Last month Lilly halted a mid-stage study of a different type of Alzheimer's treatment, from a class known as beta secretase, or BACE, inhibitors, after signs of potential liver toxicity. But the company said it remains interested in developing other BACE inhibitors.

Earlier this month, the U.S. Centers for Medicare & Medicaid Services proposed guidelines that would deny reimbursement for Amyvid unless patients are taking part in one of several clinical trials in which the $3,000 test is being used.

In the meantime, two independent studies of solanezumab are just getting off the ground, and could shed further light on the drug's potential.

They involve a study of elderly patients who do not yet have symptoms of Alzheimer's but who have deposits of amyloid in their brains, and a study of patients with an inherited high risk of developing Alzheimer's.

(Reporting by Ransdell Pierson; Editing by Lisa Von Ahn, Julie Steenhuysen and Sofina Mirza-Reid)

Source: http://news.yahoo.com/lilly-plans-big-alzheimers-disease-study-prior-failures-130413774.html

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Wednesday, July 10, 2013

Republicans accuse Obama of exceeding authority

WASHINGTON (AP) ? In the courts of law and public opinion, congressional Republicans increasingly accuse President Barack Obama of exceeding his constitutional authority for the benefit of special interests, most recently by delaying a requirement for businesses to provide health care for their workers.

In one instance, Senate Republicans formally backed a lawsuit challenging the president's appointment of three members of the National Labor Relations Board without confirmation. The Supreme Court has agreed to review a ruling in the case, which found that Obama overstepped his bounds.

Most recently, the White House's decision to postpone a key part of the president's health care law drew rhetorical denunciations Tuesday from Republicans who, ironically, want to see the law repealed in its entirety.

Senate Republican leader Mitch McConnell of Kentucky said the action was part of a pattern of "indifference to the rule of law on the part of this administration. ... He did it with immigration. He did it with welfare work requirements. And he did it with the NLRB when he took it upon himself to tell another branch of government when it was in recess.

"And now he's doing it again with his own signature health care law," said McConnell, who is seeking re-election next year in a state where Obama is unpopular.

White House press secretary Jay Carney had no comment on McConnell's complaint that the administration is indifferent to the rule of law. The White House disputes each allegation in turn, citing specific legal authority for the president's actions, or saying the assertion was factually incorrect.

Oddly enough, on one particularly incendiary issue, Obama so far has rejected suggestions that he has authority to continue government borrowing without a vote by Congress to raise the debt ceiling. To switch course would inevitably invite a lawsuit.

Whatever the merits of the Republican claims, they sometimes include a dose of politics of the sort they accuse Obama of playing.

Rep. Steve King, R-Iowa, threatened to sue when Obama announced several weeks before the 2012 election that he would stop deportation proceedings against many younger immigrants who are in the country illegally, so long as they went to college or served in the military. The move was widely viewed as a gesture to Hispanic voters, many of whom live in key battleground states.

A suit subsequently was filed by federal immigration enforcement agents, and King was not a party to it, although his office says it was the product of a meeting he called. King also used the issue to raise money for his own re-election to Congress last fall, emailing potential donors that Obama "refuses to enforce immigration laws."

In addition to challenging Obama's adherence to the rule of law, McConnell's speech included a pre-emptive attack in case Democrats try to change Senate rules this summer and make it easier to confirm presidential appointees.

"I know Washington Democrats are getting a lot of pressure from big labor union bosses and other far-left elements of their base to do this," the Kentucky Republican said. "These folks have told Democrats it's time to pay up, and they don't have much time for things like the democratic process or the rule of law."

He spoke at about the same time House Democrats and union leaders held a news conference to pressure Republicans not to block confirmation for several appointments, including at the NLRB, which rules on collective bargaining disputes between employees and companies.

"Whatever it takes to get these nominees through, an up or down vote is what we want," said Bill Samuel, the AFL-CIO's legislative director. "That might very well include a change in the rules to make it impossible for the Republicans to filibuster the nominations."

The lawsuit backed by Senate Republicans challenged Obama's so-called recess appointments of three members of the NLRB.

The Constitution gives the president authority to make appointments without confirmation when the Senate is in recess. In the case at issue, Obama acted at a time Congress was away on an extended holiday break, but the Senate met every three days as part of an explicit strategy by Republicans to prevent such appointments.

Rejecting the administration's arguments, a three-judge panel of the U.S. Court of Appeals in Washington, D.C., ruled that recess appointments can be made only during the once-a-year break between sessions of Congress, typically at the end of the year.

Two judges on the panel also ruled that to qualify for a recess appointment, a position must become vacant while the Senate is in recess.

Despite Republican allegations, administration officials cite specific legal authority for some of Obama's actions.

The Treasury Department said the one-year waiver of the requirement for companies to provide health insurance announced last week was "an exercise of the administrative authority" granted by law when it comes to implementing new legislation like the health care act.

One official cited other recent examples of waivers under the same authority. A case in 2011 said aviation excise taxes that had lapsed and then been reinstated would not be applied for a three-week period ending the day Congress re-enacted them.

The other, from 2007, related to standards for penalties on income tax preparers, according to the official, who citing department regulations in speaking on condition of anonymity.

A year ago, when Obama announced the shift in immigration policy, Homeland Security Secretary Janet Napolitano cited "prosecutorial discretion."

McConnell's reference to welfare relates to a charge by Republicans that the administration proposed new rules to lessen the work requirements implemented as part of a 1996 overhaul of the program. The White House denies the proposal had that effect.

___

Associated Press writers Jim Kuhnhenn and Sam Hananel contributed to this report.

Source: http://news.yahoo.com/republicans-accuse-obama-exceeding-authority-213407261.html

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Monday, July 8, 2013

Ice Above Lake Vostok Includes DNA From Animals

Microbes that live inside fish intestines are among the array of life that appear to have been found in ice drilled from above Lake Vostok, the deepest lake buried beneath Antarctica's ice sheet.

The ice is thought to be from frozen Vostok lake water, chilled by contact with the lake's overlying glacier. Called accretion ice, scientists first reported evidence of microbes in this ice in the journal Science in 1999. In some spots above the lake, the accretion ice is more than 650 feet (200 meters) thick and 20,000 years old, scientists believe. Though ice has sealed the surface for up to 15 million years, subglacial waterways may have refreshed the lake and even brought in life from outside the basin, scientists think.

Now, a new study of genetic material in the accretion ice reveals more than 3,500 unique traces of life in Lake Vostok, including animals, from a wide variety of ecosystems. Most of the snippets of DNA and RNA are from bacteria and fungi, according to the report, published July 3 in the journal PLOS ONE. Some sequences match living microbes pulled from the same ice cores by the research team in 2008 and 2009, said senior author Scott Rogers, a molecular biologist at Bowling Green State University in Ohio. [Strangest Places Where Life Is Found on Earth]

Although the researchers found genetic evidence of many different organisms in the ice, the overall concentration was incredibly low compared with water from lake systems on other continents, Rogers said, ranging between one cell to 100 cells per milliliter (0.04 ounces) of fluid. "If [Lake Vostok] does have life, it's interesting life, but it's not highly concentrated life," Rogers told LiveScience.

New view of Vostok

Lake Vostok is Antarctica's biggest and deepest subglacial lake; its surface sits 1,600 feet (500 m) below sea level. It is roughly the size of Lake Ontario and lies beneath 2 miles (3.2 kilometers) of ice. The lake basin is about 35 million years old and was entombed after Antarctica underwent a deep freeze about 15 million years ago. Signs of subglacial waterways suggest rivers, streams or floods periodically refresh the lake, so the water in the lake is much younger than 15 million years. However, Rogers estimates the accretion ice tested in the study is between 5,000 to 10,000 years old.

The ice cores analyzed in the current study have been shared and scrutinized internationally since they were extracted in the 1990s by Russian scientists. The first hints of life turned up soon after the cores were removed, such as in the series of papers published in Science in 1999.

In their new study, Rogers and his colleagues discovered genetic sequences from cold-loving extremophiles, adapted to the chilly, light-poor environment. Among the bacteria were species that live in hydrothermal vents and organisms that colonize the intestines of rainbow trout, lobsters and tubeworms.

The team also found stretches of RNA and DNA from animals such as tiny, deep-sea-living mollusks and the water flea, a small floating crustacean found in almost every permanent water body on Earth. "The organisms we've been finding are in the very, very small range. These are tiny little creatures," Rogers said.

Finding Vostok's hotspot

Reports of life from Antarctic lakes, especially from the Vostok ice cores, have been plagued by problems with contamination. In the past decade, Rogers and his team developed a painstaking decontamination technique to remove genetic contagion on the outside of the ice core while preserving the ancient DNA and RNA within, he said. The method involves a bleach wash, as well as melting, filtering and refreezing the ice.

"Contamination is still a concern, but we think the contamination methods we have developed ensure that all the external contamination has been eliminated," Rogers said.

In the future, the team plans to conduct genetic tests on additional ice cores to pin down the center of biological activity above the lake. Studies suggest the shallow part of the lake is the active zone, with the highest cell counts in ice cores from above this region, Rogers said.

"As you get further out into the lake, the cell count really drops," he said. "We're interested in finding out what's there and how they're able to live there. Life seems to find a way to survive almost everywhere on Earth that you can go."

Earlier this year, scientists exploring subglacial Lake Whillans reported the first evidence for microbial life in water retrieved from a buried lake in Antarctica. There are nearly 380 subglacial lakes, remnants of the lost world beneath the ice sheet.

Email Becky Oskin or follow her @beckyoskin. Follow us @livescience, Facebook?& Google+. Original article on LiveScience.com.

Copyright 2013 LiveScience, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://news.yahoo.com/ice-above-lake-vostok-includes-dna-animals-213622012.html

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